Intranasal immunization with acellular pertussis vaccines results in long term immunity to bordetella pertussis in mice bordetella pertussis colonizes the respiratory mucosa of humans inducing an immune response seeded in the respiratory tract an individual once convalescent exhibits long term immunity to the pathogen. Covers both the foundation concepts of immunology among the most exciting in modern biology and medicine and their application to the real world of diseases and health this new text combines clear narratives of how the immune system functions relying in many instances on supporting data from experiments the editors use examples and illustrations depicting basic immunologic processes in . Infection and immunity is a peer reviewed medical journal published by the american society for microbiology it focuses on interactions between bacterial fungal or parasitic pathogens and their hosts. Innate immunity is the first line of defense against infection there have been amazing discoveries in the field of innate immunity with lots of newly discovered cells or cell subsets that have a crucial function but innate immunity alone is not enough for us to get rid of infections