Adaptive design methods in clinical trials second edition reflects recent developments and regulatory positions on the use of adaptive designs in clinical trials it unifies the vast and continuously growing literature and research activities on regulatory requirements scientific and practical issues and statistical methodology. Adaptive design methods in clinical trials 2nd revised ed doi 101201 9781584887775 publisher chapman hall authors shein chung chow mark chang boston university second the . With new statistical and scientific issues arising in adaptive clinical trial design including the us fdas recent draft guidance a new edition of one of the first books on the topic is needed adaptive design methods in clinical trials second edition reflects recent developments and regulatory positions on the use of adaptive designs in clinical trials it unifies the vast and . 2013 adaptive design methods in clinical trials second edition by s c chow and m chang journal of biopharmaceutical statistics vol 23 no 2 pp 493 495. Adaptive design methods in clinical trials second edition chapman hallcrc biostatistics series is available in our digital library an online access to it is set as public so you can download it instantly our books collection spans in multiple countries allowing you to get the most less latency time to download any of our books like this one